Mark Twain - Racism †Huckleberry Finn Essay Example for Free

Mark Twain Racism – Huckleberry Finn Essay Mark Twain depicts an apprehension to racisms through the character Huckleberry Finn. He is a white young boy who comes in contact with the conditions of slavery at a relatively early age. The author allows him to feel uncomfortable with the very process by which humans are classified in civil society. This view is based on how Twain created the institution of slavery to be established at the time. Twain in emphasizing his views allow his character to be confronted by situations which would force him to think about slavery and the face of racism. The young man is pressured by his own father’s harsh racist belief as depicted in the election scene, â€Å"It was ‘lection day, and I was just about to go and vote myself if I warn’t too drunk to get there; but when they told me there was a State in this Country where they’d let a nigger vote, I drawed out. † (Echeat, 2010)Twain creates the paradox between father and son to highlight where he stood on racism. Mark Twain-Racism-Tom Sawyer Surprisely, even though Mark Twain’s Adventures of Tom Sawyer includes a character named Huckleberry Finn as is represented in The Adventures of HucleburyFinn the role designation is entirely different. Huckleberry Finn plays a supportive role in allowing Tom to complete his mischiefs. The author displayed very little interest of projecting a race issues his that society. Its only emergence was flashed as a minor development in the story was in the killing of Dr Robinson by a Native American, However, there were no direct racial insinuations in the account, ‘ In the scuffle, Injun Joe stabs Dr. Robinson with Potter’s knife†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. Native-American â€Å"half-breed† Injun Joe. ’(Sparknotes, 2010) To conclude It can be presumed that the time when Huckleberry Finn was written racism was Mark Twain’s major sociological concern. On the other hand with Tom Sawyer he was viewing morals from the perspective of parental authority and how social groups interact. REFERENCE Racism in Huckleberry finn. www. echeat. com. N. p. , n. d. Web. 29 May 2010. http://www. echeat. com/essay. php? t=33441. The Adventures of Tom Sawyer. www. sparknotes. com. N. p. , n. d. Web. 29 May 2010. http://www. sparknotes. com/lit/tomsawyer/summary. html.

The Media Should NOT Define our Self-Image Essays -- Adverts, Advertis

Do we choose to define ourselves? Everyday we turn on the television; we are subjected to advertisements about what we are supposed to be, what we are supposed to wear, and even what we are supposed to drive. Ultimately we choose the vehicles we drive, but the media has a huge influence on us. Three television advertisements reveal the vehicles women and men are believed to drive. The Honda Odyssey is shown in advertisements with a woman driving around kids to their daily functions. The Ford F150 and the Chevy Silverado are shown with men four wheeling through the hills. Advertisements tell us what roles we are â€Å"supposed† to play in society. In reality men and women’s roles in society have greatly changed from the past, but television advertisements do not represent these changes. Vans are depicted as â€Å"mom vehicles† and trucks are â€Å"dad or man vehicles.† When a vehicle manufacturer comes out with a new model of van they usually depict a women driving around, with a vehicle full of kids. She drops the kids off and picks them up, she then proceeds to move around all of the seats illustrating to the consumer all that this new van has to offer. It is all work and no play for moms in the working world. When a new model of the Ford F150 or the Chevy Silverado comes out, advertisements usually depict a man four-wheeling through the hills demonstrating the durability and power of the vehicle. Ford’s motto is â€Å"Built Ford Tough† and Chevy’s motto is â€Å"Like a Rock.† Thes...

Ibuprofen and Acetaminophen Essay

Organic chemical compounds contain a vast number of isomers, molecules with the same molecular formula but different atomic arrangement, of which there are three types: structural, geometric and optical. The most closely-linked of isomers are optical isomers, which differ only by the three-dimensional placement of the molecule’s attachments, which renders its mirror images to be non-superimposable. The presence of optical isomerism within a molecule is determined by the existence of a chiral centre—a carbon atom with four different groups (see Appendix, figure 1). Pure optical isomers have identical physical properties such as melting point, boiling point and density, as well as identical chemical properties; thus there are only two ways that they can be distinguished: their interaction with other chiral substances and their interaction with plane polarized light. An enantiomer (one out of a pair of optical isomers) rotates plane polarized light in the opposite direction of which the other enantiomer rotates the plane polarized light, of equal magnitude (see Appendix A, figure 2). An enantiomer that shifts plane polarized light to the left is given the prefix â€Å"L† (levorotatory) or â€Å"S†, while an enantiomer that shifts plane polarized light to the right is given the prefix â€Å"D† (dextrorotatory) or â€Å"R†. Despite their physical and chemical similarities, optical isomers are known to have substantially different behaviours within the human body. This is due to the fact that enzymes and receptors in the body are stereospecific, meaning that they can interact with one enantiomer of certain molecules and not the other. For instance, the human body can only break down D-glucose (dextrose) for energy but not L-glucose, and can only utilize L-amino acids rather than D-amino acids. While one form of a stereoisomer may be beneficial, the other may be ineffective or even harmful, in some cases. Thus, it is crucial that optical isomerism is taken into account during medicinal drug development and usage. For example, the sedative thalidomide was available in Europe in the 1960s for purposes of alleviating morning sickness in pregnant women. However, the drug was sold as a racemic mixture, which contains equal portions of both enantiomers (this would not shift plane polarized light as the two enantiomers shift in different directions),  and while R-thalidomide (see Appendix A, figure 3) works effectively as a sedative; S-thalidomide can cause genetic damage leading to mutation of the fetus. Consequently, 12 000 infants were born worldwide with malformation of the limbs. To further illustrate the importance of optical isomers in drug action, the drug ibuprofen can be explored. Ibuprofen is a drug used for anti-inflammatory purposes such as pain relief, fever and swelling reduction, and is classified as a nonsteroidal anti-inflammatory drug (NSAID). Derived from propanoic acid in the 1960s by a pharmacy chain called Boot’s UK Limited, ibuprofen was initially launched as a treatment for rheumatoid arthritis, and was awarded the Queen’s Award for Technical Achievement in 1987. It is currently available under a variety of trademarks such as Advil, Motrin, Nurofen, and Brufen, among others. Ibuprofen works by inhibiting the enzymatic action of cyclooxygenase (COX1 and COX2) within the body, which catalyzes the conversion of a compound called arachidonic acid into prostaglandins. Prostaglandins are locally-acting hormones that cause swelling, heat, loss of function, fever and pain, collectively known as inflammation, at a site of injury through the accumulation of white blood cells. Through inhibiting this reaction, painful symptoms can be reduced or eliminated. The IUPAC name for ibuprofen is 2-(4-(2-methylpropyl) phenyl) propanoic acid. It is a carboxylic acid which also contains a phenyl group (see Appendix A, figure 5). Due to its chirality, ibuprofen has two enantiomers (see Appendix A, figure 6): S-ibuprofen, which rotates plane polarized light to the left and is pharmacologically active, and R-ibuprofen, which rotates plane polarized light to the right and has no anti-inflammatory effect (and is thus inactive as a drug, since . However, ibuprofen is sold on the market as a racemic mixture. Thus, a dose of ibuprofen contains only 50% of the active enantiomer, S-ibuprofen. Nevertheless, R-ibuprofen undergoes species-specific chiral inversion within the body, in which approximately 60% of R-ibuprofen is converted into S-ibuprofen. The mechanism of the inversion is through an enzyme, alpha-methylacyl-CoA racemase (AMACR) that is present in the liver, the kidney and gastrointestinal tract. A  substitution nucleophilic bimolecular (SN2) r eaction must take place (see Appendix B, figure 1), which results in the complete conversion of every molecule of one enantiomer to the other. In this case, only R-ibuprofen is converted into S-ibuprofen (see Appendix B, figure 2). The benefits associated with ibuprofen use include its efficiency as a NSAID in decreasing inflammation, in addition to be non-addictive and affordable. However, ibuprofen often causes stomach irritation, and can impede concentration and cause drowsiness. It may also result in a variety of adverse side effects (see Appendix C, figure 1). An alternative to ibuprofen is the drug acetaminophen, also known as paracetamol. Acetaminophen, (see Appendix A, figure 7), is commercially available under brand names such as Tylenol and Anacin (see Appendix A, figure 8). It works by inhibiting the synthesis of prostaglandins. It does not, however, have any anti-inflammatory action and thus only targets tissue of the nervous system—easing pain without being directed towards the root of the problem. Acetaminophen is known to cause fewer side effects than ibuprofen; however for a list of side effects, see Appendix C, figure 2. Acetaminophen does not have a chiral centre, and therefore does not have any optical isomers. Both drugs are used to relieve headache pains and fever; however their varying properties impact their function and effectiveness in treating specific symptoms. The solubility of ibuprofen in water is 0.0002M. Although its carboxyl functional group is highly polar, the large non-polar component greatly decreases its overall polarity. As â€Å"like dissolves like†, ibuprofen does not dissolve well in water, which is polar. To solve this problem, ibuprofen is reacted with the amino acid lysine (see Appendix A, figure 9), which together forms the salt ibuprofen lysinate. Ibuprofen is then released into the bloodstream in which the reaction can reverse. On the other hand, acetaminophen is highly soluble in water; with a solubility of 0.091M. Because it contains an amide and an alcohol, there is a substantial degree of hydrogen bonding resulting in high polarity (see Appendix A, figure 10). This allows the drug to be absorbed into the bloodstream effectively. Ibuprofen has a pKa (acid dissociation constant) of approximately 4.43, while the pKa of acetaminophen is 9.51 and 25 °C, making ibuprofen more acidic. Because neutral substances pass through bodily membranes more easily, acetaminophen is more easily absorbed. Acetaminophen also has more acid stability. Administered orally, an ibuprofen capsule has an enteric coating, which prevents stomach acid from breaking down the drug before it reaches the small intestine, where it is absorbed. A film coating is used on a tablet of acetaminophen, which protects the tongue from the contents, as well as protecting the contents from moisture and light. Within the body, the film can be broken down by saliva or stomach acid, and the way in which the drug is absorbed is not affected. Appendix A: Images Figure 1: Molecule with a chiral centreFigure 2: Plane polarized light beamed through a filter. The two enantiomers shift light in opposite directions. Figure 1: Type of isomer vs. molecule melting and boiling point Type of Isomers Molecules Melting Point and Boiling Point Structural Isomers butane 2-methylpropane MP: -140 °C BP: -1 ° C MP: -159.6 °C BP: -11.7  °C Geometric Isomers cis-butene trans-butene MP: -138.9  °C BP: 3.7  ºC MP: -105.5  °C BP: 0.9  °C Optical Isomers L-2-butanol D-2-butanol MP: -115  °C BP: 98-100  °C MP: -115  °C BP: 98-100  °C Figure 3: The two optical isomers of thalidomide. R-thalidomide works effectively as a sedative, while S-thalidomide can damage the fetus. Figure 5: Skeletal diagram of ibuprofen, with the functional group labeled Appendix A (cont’d): Images Figure 6: Optical isomers of ibuprofen; S-ibuprofen is on the left and R-ibuprofen is on the right Figure 7: Skeletal diagram of acetaminophen, with the functional groups labeled Figure 9: Skeletal diagram of the amino acid lysine, which is reacted with ibuprofen in order to allow it to ultimately dissolve into the bloodstream Figure 10: Polarity of ibuprofen vs. acetaminophen Appendix B: Reactions Figure 1: The process of a substitution nucleophilic bimolecular (SN2) reaction Figure 2: â€Å"The mechanism of the enzymatic [chiral] inversion of R-ibuprofen (42) into S-ibuprofen. At first, the carboxylic acid is converted into an intermediate thioester (43a) by acyl-CoA ligase†¦ [This] is then converted to the opposite configuration by an epimerase, and the resultant thioester (43b) is hydrolyzed by a hydrolase, releasing S-ibuprofen.† Appendix C: Tables Figure 1: Side effects of ibuprofen Mild side effects include: upset stomach, mild heartburn, diarrhea, constipation; bloating, gas; dizziness, headache, nervousness; skin itching or rash; blurred vision Serious side effects include: chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance; black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds; swelling or rapid weight gain; urinating less than usual or not at all; nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; bruising, severe tingling, numbness, pain, muscle weakness; or severe headache, neck stiffness, chills, increased sensitivity to light, and/or seizure (convulsions). Figure 2: Side effects of acetaminophen Mild side effects include: drowsiness Serious side effects include: low fever with nausea, stomach pain, and loss of appetite; dark urine, clay-colored stools; or jaundice (yellowing of the skin or eyes) liver failure (with overdose) Bibliography CHAPTER 5: RULES FOR SPECIFICATION OF CHIRALITY. (n.d.). University of Illinois at Chicago-Chemistry. Retrieved October 8, 2013, from tigger.uic.edu/~kbruzik/text/chapter5.htm This source is credible because it is a university website. Chemistry in your cupboard | Nurofen . (n.d.). Royal Society of Chemistry | Advancing excellence in the chemical sciences. Retrieved October 10, 2013, from http://www.rsc.org/learn-chemistry/resources/chemistry-in-your-cupboard/nurofen/3 This source is credible because it is a reputable educational society in Britain. Clancy, C., Farrow, K., Finkle, T., & Francis, L. (2002). McGraw-Hill Ryerson chemistry 12. Toronto: McGraw-Hill Ryerson. This is credible because it is a textbook used in class. Cohen, J. S. (2007, December 4). The Little-Known Dangers of Acetaminophen.Life Extension. Retrieved October 10, 2013, from http://www.lef.org/magazine/mag2007/dec2007_report_acetaminophen_02.htm This is credible because it is health journal from a reputable organization. Ibuprofen. (2013, July 18). Livertox: Clinical and Research Information. Retrieved October 10, 2013, from http://livertox.nih.gov/Ibuprofen.htm This is credible because it is from the United States government. Open Notebook Science. (2013, October 10). Solubility of ibuprofen in organic solvents. Retrieved October 8, 2013, from http://lxsrv7.oru.edu/~alang/onsc/solubility/allsolvents.php?solute=ibuprofen This is credible because it is an educational institution. 1C – http://www.fda.gov/ohrms/dockets/ac/02/briefing/3882b2_06_international%20ibuprofen%20foundation.htm 2C – http://www.lef.org/magazine/mag2007/dec2007_report_acetaminophen_02.htm http://books.google.ca/books?id=9xYuQKZSDkIC&pg=PA205&lpg=PA205&dq=how+is+r-ibuprofen+converted+into+s-ibuprofen&source=bl&ots=D4iuQfKoyT&sig=WS9y5uMJa0Hr68Og5FhkJr73OfQ&hl=en&sa=X&ei=WcZVUoqJDpCi4APKyoDoBg&ved=0CFcQ6AEwBQ#v=onepage&q=how%20is%20r-ibuprofen%20converted%20into%20s-ibuprofen&f=false 2B – http://books.google.ca/books?id=Zgx13oMZaYUC&pg=PA363&lpg=PA363&dq=how+is+r-ibuprofen+converted+into+s-ibuprofen&source=bl&ots=sWD8D0j8HI&sig=L_5r42H68KotX

Reading Comprehension When Applying for a Job

The perfectly composed resume will fail to impress an HR professional unless it underscores the skills and experience your prospective employer needs. To determine what the company is looking for, you must learn how to search for the clues in the job posting. Then, you can tailor your resume and cover letter.   To test your job post comprehension  read the following advertisements and answer the questions below: Needed: Full-time secretary position available. Applicants should have at least 2 years experience and be able to type 60 words a minute. No computer skills required. Apply in person at United Business Ltd., 17 Browning Street.Are you looking for a part-time job? We require 3 part time shop assistants to work during the evening. No experience required, applicants should between 18 and 26. Call 366 - 76564 for more information.Computer trained secretaries: Do you have experience working with computers? Would you like a full-time position working in an exciting new company? If your answer is yes, give us a call at 565-987-7832.Teacher Needed: Tommys Kindergarten needs 2 teacher/trainers to help with classes from 9 a.m. to 3 p.m. Applicants should have appropriate licenses. For more information visit Tommys Kindergarten in Leicester Square No. 56.Part Time work available: We are looking for retired adults who would like to work part-time at the weekend. Responsibilities include answerin g the telephone and giving customers information. For more information contact us by calling 897-980-7654.University positions open: The University of Cumberland is looking for 4 teaching assistants to help with homework correction. Applicants should have a degree in one of the following: Political Science, Religion, Economics or History. Please contact the University of Cumberland for more information. Comprehension Questions Which position is best for these people? Choose ONLY ONE position for each person. Jane Madison. Jane recently retired and is looking for a part-time position. She would like to work with people and enjoys public relation work. The best job for Jane is _____Jack Anderson. Jack graduated from the University of Trent with a degree in Economics two years ago. He would like an academic position. The best job for Jack is _____Margaret Lillian. Margaret is 21 years old and would like a part-time position to help her pay her university expenses. She can only work in the evenings. The best job for Margaret is _____Alice Fingelhamm. Alice was trained as a secretary and has six years of experience. She is an excellent typist but does not know how to use a computer. She is looking for a full-time position. The best job for Alice is _____Peter Florian. Peter went to business school and studied computer and secretarial skills. He is looking for his first job and would like a full-time position.​​ The best job for Peter is ____Vincent san George. Vincent loves work ing with children and has an education license from the city of Birmingham. He would like to work with young children. The best job for Vincent is _____ Once youve found the best job for each person, check your answers below. Answers Which position is best for these people? Jane Madison. Jane recently retired and is looking for a  part-time position. She would like to work with people and enjoys public relation work. The best job for Jane is  5Jack Anderson. Jack graduated from the University of Trent with a degree in Economics two years ago. He would like an academic position. The best job for Jack is  6Margaret Lillian. Margaret is 21 years old and would like a part-time position to help her pay her university expenses. She can only work in the evenings. The best job for Margaret is  2Alice Fingelhamm. Alice was trained as a secretary and has six years of experience. She is an excellent typist but does not know how to use a computer. She is looking for a  full-time position. The best job for Alice is  1Peter Florian. Peter went to business school and studied computer and secretarial skills. He is looking for his  first job  and would like a  full-time position. The best job for Peter is  3Vincent san George. Vincent loves working w ith children and has an education license from the city of Birmingham. He would like to work with young children. The best job for Vincent is  4